Scientific Software Technologies Center (SSTC) was founded in 1997 to
concentrate efforts on the development of new powerful mathematical algorithms
and creation of complete software solutions for analysis of fluorescence
measurements data (fluorescence correlation spectroscopy data, time-resolved
fluorescence and anisotropy data, time-resolved frequency domain data, etc.).
In 1998 first version of Fluorescence Data Processor (FDP) was released. The Fluorescence Data Processor (FDP) was developed as a tool for managing and analyzing the data obtained from time-resolved fluorescence decay measurements.
Also in 1998 SSTC developers group started to work in Fluorescence Correlation Spectroscopy field;
In 1999 FDP was updated to Time-Resolved Fluorescence and Anisotropy Data Processor (TRFADP)
software. This new version of the software was designed as a complete solution
for managing and analysis of data obtained from time-resolved fluorescence decay
measurements. In the same year SSTC extended its activities in FCS field. In January - April of 1999 SSTC in close collaboration with Carl Zeiss developed the analysis part of fitting software that is distributed with ConfoCor 2. In the same year SSTC started to create its own software designed for analysis of FCS data.
In April 2000 FCS Data Processor (FCSDP) version 1.2 was released. This software represented the first SSTC solution for global analysis of FCS data. This software package was designed as a powerful tool for managing and fitting large amount of measured data in FCS field.
In 2000 - 2001 SSTC developed the Time-Resolved Fluorescence and Anisotropy Global Analysis Program for Katholieke Universiteit Leuven.
In December 2001 new version of FCSDP was released. This version allows
calculation almost all statistical characteristics from Raw Data. Also this version provides possibility to create user-defined models written on build-in Script Programming Language. This feature can be efficiently used by model developers for creating and testing new analytical models.
In 2002-2003 the Time-Resolved Frequency Domain Fitting Software (TRFDFS) providing the global analysis of variable-frequency phase shift data was developed in collaboration with University of Bern, Switzerland.
In 2003 the BIFL Data Analyzer (BIFLDA) software intended for sliding analysis of fluorescence decays and correlation curves calculated from BIFL data was created in collaboration with Katholieke Universiteit Leuven, Belgium. The data for analysis can be obtained either from polarized measurements with two detectors collecting 0 and 90 degrees traces or from two detectors collecting two different colors. The analysis is based on Maximum Likelihood method.
In 2006 the FCSDP was extended to Fluorescence Fluctuation Spectroscopy Data
Processor (FFSDP) by adding the ability to perform PCH, PCMH, FCA and TIFCA.
In 2009 the TRFA Data Processor was substantionally extended and renamed to TRFA Data Processor Advanced. It supports both MLE and LS methods, more analysis models and fit quality criteria.
Besides developing software products for analysis of fluorescence spectroscopy data
members of SSTC group also have actively participated in research of algorithms
and methods that can improve the performance of analysis software.